Browsing by Author "Pinarbasi, E"
Now showing items 1-6 of 6
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A highly sensitive and specific enzyme-linked immunosorbent assay of antibodies to hepatitis C virus
Eroglu, C; Yildiz, E; Ozturk, M; Pinarbasi, E (SLOVAK ACADEMIC PRESS LTD, 2000)In this study, a 178 amino acids long portion of the hepatitis C virus (HCV) core gene was cloned sequenced expressed in Escherichia coli, and purified. The resulting antigen (C178) was tested with human sera enzyme-linked ... -
Molecular characterization of a full genome Turkish hepatitis C virus 1b isolate (HCV-TR1): A predominant viral form in Turkey
Yildiz, E; Oztan, A; Sar, F; Pinarbasi, E; Cetin-Atalay, R; Akkiz, H; Ozturk, M (KLUWER ACADEMIC PUBL, 2002)Based on direct sequencing information from 5'UTR and NS5B regions, we identified subtype 1b as a predominant hepatitis C virus genome in Turkey, which affected more than 91% of 79 patients studied. Next, the full genome ... -
No association of polymorphisms in the glutathione S-transferase genes with pre-eclampsia, eclampsia and HELLP syndrome in a Turkish population
Cetin, M; Pinarbasi, E; Percin, FE; Akgun, E; Percin, S; Pinarbasi, H; Gurlek, F; Cetin, A (BLACKWELL PUBLISHING ASIA, 2005)Aim: There is substantial evidence that genetic factors play a role in pre-eclampsia. The aim of this study was to determine whether genetic variability in the encoding of genes for glutathione S-transferase M1 (GSTM1) and ... -
Recombinant alpha and beta subunits of M.AquI constitute an active DNA methyltransferase
Pinarbasi, H; Pinarbasi, E; Hornby, D (SPRINGER SINGAPORE PTE LTD, 2002)AquI DNA methyltransferase, M.AquI, catalyses the transfer of a methyl group from S-adenosyl-L-methionine to the C5 position of the outermost deoxycytidine base in the DNA sequence 5'CYCGRG3'. M.AquI is encoded by two ... -
The small subunit of M center dot AquI is responsible for sequence-specific DNA recognition and binding in the absence of the catalytic domain
Pinarbasi, H; Pinarbasi, E; Hornby, DP (AMER SOC MICROBIOLOGY, 2003)AquI DNA methyltransferase (M (.) AquI) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the CS position of the outermost deoxycytidine base in the DNA sequence 5`-CCCGGG-3'. M (.) AquI is a heterodimer ... -
Strong association between the GSTM1-null genotype and lung cancer in a Turkish population
Pinarbasi, H; Silig, Y; Cetinkaya, O; Seyfikli, Z; Pinarbasi, E (ELSEVIER SCIENCE INC, 2003)Glutathione S-transferases are possibly related to the detoxification of many xenobiotics involved in the etiology of cancer. To investigate the role of the glutathione S-transferase M1 deletion (GSTM1-null) in lung cancer, ...